PRION PROTEIN IS A KEY DETERMINANT OF ALCOHOL SENSITIVITY THROUGH THE MODULATION OF N-METHYL-D-ASPARTATE RECEPTOR (NMDAR) ACTIVITY.

Prion protein is a key determinant of alcohol sensitivity through the modulation of N-methyl-D-aspartate receptor (NMDAR) activity.

The prion protein (PrP) is WHEY FAC absolutely required for the development of prion diseases; nevertheless, its physiological functions in the central nervous system remain elusive.Using a combination of behavioral, electrophysiological and biochemical approaches in transgenic mouse models, we provide strong evidence for a crucial role of PrP in a

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Chitinase A, a tightly regulated virulence factor of Salmonella enterica serovar Typhimurium, is actively secreted by a Type 10 Secretion System.

As a facultative intracellular pathogen, Salmonella enterica serovar Typhimurium is one of the leading causes of food-borne diseases in humans.With the ingestion of fecal contaminated food or water, S.Typhimurium reaches the Gun Grease intestine.Here, the pathogen efficiently invades intestinal epithelial cells of the mucosal epithelium by the use

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